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This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:This medication is used short-term in people with a certain type of bleeding disorder (hemophilia) to prevent and reduce bleeding from having a tooth pulled (extraction). It is also used in people with other high-risk bleeding conditions to control bleeding at such times as after surgery or an injury, during heavy nosebleeds, or during heavy menstrual bleeding.Tranexamic acid works by helping the blood clot normally to prevent and stop prolonged bleeding. It belongs to a class of drugs known as anti-fibrinolytics.How to use Tranexamic Acid OralTake this medication by mouth, usually 2 to 4 times daily or as directed by your doctor.The dosage and length of treatment is based on your medical condition and response to treatment. Dosage is also based on your weight. Do not increase your dose, take it more frequently, or take it for a longer time than prescribed.Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.Tell your doctor if your condition persists or worsens.
This medication is used to treat eye infections. Tobramycin belongs to a class of drugs called aminoglycoside antibiotics. It works by stopping the growth of bacteria.This medication treats only bacterial eye infections. It will not work for other types of eye infections. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.How to use Tobramycin Sulfate OphtTo apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.Do not wear contact lenses while you are using this medicine. Sterilize contact lenses according to manufacturer's directions and check with your doctor before using them.Tilt your head back, look upward and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place one drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of your eye (near the nose) and apply gentle pressure. This will prevent the medication from draining out. Try not to blink and do not rub your eye. Repeat these steps for your other eye if so directed, and if your dose is for more than 1 drop.Do not rinse the dropper. Replace the dropper cap after each use.If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 to 10 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. Continue to use this medication for the full time prescribed even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.Inform your doctor if your condition persists or worsens.Tobramycin Sulfate Opht is used to treat the following:Combined Inflammation of Cornea and Conjunctiva of the Eye, Inflammation of Eyelid Edges and the Lining of the Eye, Inflammation of the Lining of the Eye due to Bacteria, Bacterial Infection of the Eyelid, Inflammation of One of the Glands of the Eyelids, Inflammation of the Sac in which Tears are CollectedTobramycin Sulfate Opht may also be used to treat: Inflammation of the Cornea due to Exposure to the Air, Inflammation of Cornea due to Improper Closing of the Eye, Infection Confined to the Surface of the Eye
ELTROXIN contains the active ingredient levothyroxine.ELTROXIN is used to treat hypothyroidism, a disease in which the thyroid gland is underactive and does not produce enough thyroxine, a hormone, which is important for controlling your metabolism. Symptoms of hypothyroidism include tiredness, muscle weakness, cramps, feeling the cold, a slow heart rate, dry and flaky skin, hair loss, a deep husky voice and weight gain.ELTROXIN is also used to treat children born with hypothyroidism (congenital), those who develop hypothyroidism in the first year of life (neonatal) and children who have hypothyroidism as part of juvenile myxoedema, a condition in which the amount of thyroxine produced by the body is low.ELTROXIN belongs to a small group of medicines called thyroid hormones, which work by replacing the body's low levels of thyroxine. Spironolactone is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; and in patients with edema (fluid retention) caused by various conditions, including heart, liver, or kidney disease. Spironolactone is also used alone or with other medications to treat high blood pressure. Spironolactone is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine, but reduces the loss of potassium from the body.Furosemide, a 'water pill,' is used to reduce the swelling and fluid retention caused by various medical problems, including heart or liver disease. It is also used to treat high blood pressure. It causes the kidneys to get rid of unneeded water and salt from the body into the urine.Spironolactone/Furosemide comes as a tablet to take by mouth. It usually is taken once a day in the morning or sometimes twice a day . Take Lasilactone at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take spironolactone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Your doctor may start you on a low dose of Lasilactone and gradually increase your dose. Lasilactone controls high blood pressure and hyperaldosteronism, but does not cure these conditions.. It may take about 2 weeks or longer before the full effect of spironolactone occurs. Continue to take spironolactone even if you feel well. Do not stop taking spironolactone without talking to your doctor.Lasilactone combination with other medicines to treat precocious puberty (a condition causing children to enter puberty too soon, resulting in the development of sexual characteristics in girls usually younger than 8 years of age and in boys usually younger than 9 years of age) or myasthenia gravis (MG, a disease in which the nerves do not function properly and patients may experience weakness; numbness; loss of muscle coordination; and problems with vision, speech, and bladder control). Lasilactone also may be used to treat certain female patients with abnormal facial hair. Talk to your doctor about the possible risks of using this medication for your condition. This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:This medication is a beta-blocker used to treat chest pain (angina) and high blood pressure. It is also used after an acute heart attack to improve survival. High blood pressure reduction helps prevent strokes, heart attacks and kidney problems.This drug works by blocking the action of certain natural chemicals in your body such as epinephrine on the heart and blood vessels. This results in a lowering of the heart rate, blood pressure, and strain on the heart.OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This medication may also be used for irregular heartbeats, heart failure, migraine headache prevention, tremors and other conditions as determined by your doctor.How to use Atenolol OralTake this medication by mouth, usually once daily; or as directed by your doctor. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day.This drug is not effective if you use it only when chest pain or a migraine headache occurs. It is very important to take this medication regularly as prescribed to help prevent these conditions.The dosage is based on your medical condition and response to therapy. It may take one or two weeks before the full benefit of this drug takes effect. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.Do not suddenly stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Refer to the Warning section.Atenolol Oral is used to treat the following:High Blood Pressure, Heart Attack, AnginaAtenolol Oral may also be used to treat: Additional Medications for Treating Pheochromocytoma, Overactive Thyroid causing Life-Threatening Symptoms, Essential Tremor, Migraine Prevention, Acute Syndrome of the Heart, Mitral Valve Prolapse Syndrome, Hypertrophic Cardiomyopathy, Prevention of Congenital Long QT Syndrome associated Ventricular Arrhythmia, Rapid Ventricular Heartbeat, Prevention of Recurrent Atrial Fibrillation, Ventricular Rate Control in Atrial Fibrillation, Supraventricular Cardiac Arrhythmia, Chronic Heart Failure, Diastolic Heart Failure
DAKTARIN is a medicine used for treating athlete's foot, tinea, ringworm and thrush infections ofthe skin caused by fungi, including yeast.Do not use DAKTARIN if you know you are allergic to:* miconazole or any of the ingredients (see the last section ofthis leaflet for a full list of ingredients)* similar antifungal agents such as ketoconazole.Do not use DAKTARIN if:* you are pregnant orbreastfeeding, unless your doctorhas advised you to* the packaging is torn or showssigns of being tampered with* the expiry date (month and year)printed on the pack has passed. If you take it after the expiry date it may not work This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:Dideral contains the active ingredient propranolol, which is a type of medicine called a beta-blocker. (NB. Propranolol is also available without a brand name, ie as the generic medicine.) Beta-blockers work by blocking beta receptors that are found in various parts of the body. Blocking beta receptors prevents the action of two chemicals, called noradrenaline and adrenaline, which are produced naturally by the body. These are often referred to as the 'fight or flight' chemicals, because they are responsible for the body's reaction to stressful situations.Beta receptors are found in the heart. When they are blocked by propranolol the heart is made to beat more slowly and with less force. This reduces the pressure at which the blood is pumped out of the heart and around the body. This in turn reduces blood pressure, which means that propranolol can be used to treat high blood pressure. It also reduces the energy used by the heart to pump blood around the body, and so reduces the heart's need for oxygen, which means it can also be used in the management of angina. Angina is chest pain that occurs because the heart does not get enough oxygen to meet demand, such as when doing exercise. Propranolol reduces the workload of the heart and so decreases its demand for oxygen. This helps to prevent attacks of angina.Propranolol is also prescribed to people who have had a heart attack, because its effects on the heart have been shown to decrease the likelihood of having a further heart attack, and to lower the risk of continued illness and death.Slowing the heart rate also helps to control abnormal heart beats called arrhythmias. Arrhythmias can seriously undermine the pumping action of the heart and result in inefficient blood circulation around the body. Propranolol corrects the abnormal heart beat and thus can be used to treat arrhythmias.In addition to these heart related uses, propranolol can also be used to control symptoms that are associated with anxiety or an overactive thyroid gland (thyrotoxicosis), such as a racing pulse, sweating and tremor. This is because it blocks the effects of adrenaline. Propranolol is also used to prevent migraine, although it is not fully understood how propranolol works in this area.Syprol is a liquid brand of propranolol.What is it used for? High blood pressure (hypertension) Angina pectoris Irregular heart beats (arrhythmias)Heart disease characterised by thickening of the internal heart muscle and a blockage inside the heart (hypertrophic obstructive cardiomyopathy)Prevention of further heart attacks following an initial heart attack Management of thyrotoxicosis and thyrotoxic crisis (with other medicines) Anxiety Tremor without underlying cause (essential tremor)Pre-surgical management of adrenal gland tumours (phaeochromocytoma), but only in combination with an alpha-blocking medicinePreventing bleeding from varicose veins in the foodpipe (oesophageal varices) that occur due to high blood pressure in the vein taking bood from the gut to the liver (portal hypertension) - usually a result of liver cirrhosis Prevention of migraines This drug belongs to a group of medications called ACE inhibitors. It is used to treat high blood pressure (hypertension) in adults and in children 6 years of age and older. It works by relaxing blood vessels, causing them to widen. High blood pressure reduction helps prevent strokes, heart attacks and kidney problems.This medication is also used after an acute heart attack to improve survival, and is used with other drugs (e.g., "water pills"/diuretics, digoxin) to treat congestive heart failure.OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This medication may also be used to help protect the kidneys from damage due to diabetes.How to use Lisinopril OralTake this medication by mouth, usually once a day or as directed by your doctor. You may take this drug with or without food. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day.If you are taking this drug in the liquid suspension form, shake the bottle well before each use. Measure the dose out carefully.Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can raise your potassium levels, which rarely can cause serious side effects such as muscle weakness or very slow heartbeats. Tell your doctor immediately if these effects occur.The dosage is based on your medical condition and response to therapy. For the treatment of high blood pressure, it may take 2 to 4 weeks before the full benefit of this drug occurs. It may take several weeks or months to see the full benefit when this drug is used for congestive heart failure.It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:This medication is used to treat fungal infections of the mouth. Nystatin is an antifungal that works by stopping the growth of fungus.Nystatin suspension should not be used to treat fungal infections of the blood.How to use Nystatin OralShake well before using, and use the provided medication dropper to carefully measure out the dose. Unless your doctor instructs you otherwise, use as follows: Place half of the dose in one side of the mouth. Swish it around the mouth, gargle, and swallow. Keep the liquid in your mouth for as long as possible before swallowing. Then repeat with the remaining half of the dose in the other side of the mouth. Avoid eating for 5-10 minutes after using this medication.Use this medication 4 times a day or as directed by your doctor. It may take from several days to several months to complete treatment. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. Dosage is based on your medical condition and response to therapy.Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow the infection to continue, resulting in a return of the infection.Inform your doctor if your condition persists after several days of treatment or worsens at any time. Telmisartan is used alone or in combination with other medications to treat high blood pressure. Telmisartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain chemicals that tighten the blood vessels, so blood flows more smoothly.Telmisartan comes as a tablet to take by mouth. It is usually taken once a day with or without food. To help you remember to take telmisartan, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take telmisartan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Your doctor may start you on a low dose of telmisartan and gradually increase your dose.Telmisartan controls high blood pressure but does not cure it. Continue to take telmisartan even if you feel well. Do not stop taking telmisartan without talking to your doctor.High blood pressure reduction helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the hormone angiotensin thereby relaxing blood vessels, causing them to widen. Telmisartan belongs to a class of drugs called angiotensin receptor blockers.OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used to treat congestive heart failure and to help protect the kidneys from damage due to diabetes.How to use Temisartan OralTake this medication by mouth, usually once daily or as directed by your doctor. You may take this drug with or without food. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day.Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can raise your potassium levels, which rarely can cause serious side effects such as muscle weakness or very slow heartbeats. Tell your doctor immediately if these effects occur.The dosage is based on your medical condition and response to therapy. For the treatment of high blood pressure, it may take 4 weeks before the full benefit of this drug occurs This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical InformationCyclo-Progynova is a hormone replacement therapy (HRT) preparation. Each pack contains two types of tablets. The white tablets contain estradiol valerate and the pale brown tablets contain estradiol valerate in combination with norgestrel. Estradiol valerate (previously spelt oestradiol valerate in the UK) and norgestrel are forms of the main female sex hormones, oestrogen and progesterone. Estradiol valerate is a naturally occuring form of oestrogen and norgestrel is a synthetic form of progesterone.WomensÆ ovaries gradually produce less and less oestrogen in the period up to the menopause, and oestrogen blood levels decline as a result. The declining levels of oestrogen can cause distressing symptoms, such as irregular periods, hot flushes, night sweats, mood swings and vaginal dryness or itching.Oestrogen (in this case in the form of estradiol valerate) can be given as a supplement to replace the falling levels in the body and help reduce these distressing symptoms of the menopause. This is known as hormone replacement therapy (HRT). HRT is usually only required for short-term relief from menopausal symptoms and its use should be reviewed at least once a year with your doctorA progestogen (in this case in the form of norgestrel) is needed as part of HRT for women who have not had a hysterectomy. This is because in women with an intact womb, oestrogen stimulates the growth of the womb lining (endometrium), which can lead to endometrial cancer if the growth is unopposed. A progestogen is given to oppose oestrogen's effect on the womb lining and reduce the risk of endometrial cancer, though it does not eliminate this risk entirely. This is known as combined HRT. Cyclo-Progynova is a sequential form of combined HRT. This means that oestrogen is taken on a continuous basis and progesterone is added for a portion of each month. The white tablets taken in the first 11 days of each Cyclo-Progynova cycle contain only estradiol. The brown tablets taken in the next 10 days of each cycle contain both estradiol and norgestrel. After these 21 days you then have a seven day tablet-free break before the next cycle is started, rather like the combined contraceptive pill. This type of HRT is more suitable for women who are still having irregular periods, because it usually results in a monthly withdrawal bleed in the pill-free week. HRT is also sometimes used to prevent osteoporosis in postmenopausal women. The declining level of oestrogen at menopause can affect the bones, causing them to become thinner and more prone to breaking. Oestrogen supplements help prevent bone loss and fractures that may occur in women in the years after menopause. However, in December 2003, a review of the available evidence on the risks and benefits of HRT by the Medicines and Healthcare products Regulatory Agency (MHRA) and the Committee on Safety of Medicines (CSM) in the UK, concluded that the risks of using HRT long-term to prevent osteoporosis in women aged over 50 years exceed the benefits. As a result, this medicine should not be used as a first-line option for preventing postmenopausal osteoporosis in women over 50. However, it may be used as a second-line option for women at high risk of fractures who cannot take other medicines that are licensed for preventing osteoporosis. Women considered to be at high risk of developing fractures following the menopause include those who have had an early menopause, those with a family history of osteoporosis, those who have had recent prolonged corticosteroid therapy (eg prednisolone), those with a small thin frame, and smokers. You can read more about the risks and benefits of HRT and other medicines for preventing osteoporosis in the factsheets about menopause and osteoporosis linked below.What is it used for? Hormone replacement therapy to relieve symptoms of the menopause.Second-line option for preventing osteoporosis in postmenopausal women who are at high risk of fractures and cannot take other medicines licensed for preventing osteoporosis. Pilocarpine is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Pilocarpine relieves the symptoms of glaucoma.Pilocarpine comes in eyedrops, eye gel, and a controlled-release system (Ocusert Pilo). The eyedrops usually are applied two to four times daily. The gel usually is applied once daily and at bedtime. The controlled-release system is used once a week and should be applied at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use pilocarpine exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.Pilocarpine controls glaucoma, but does not cure it. Continue to use pilocarpine even if you feel well. Do not stop using pilocarpine without talking to your doctor.To use the eyedrops, follow these steps: Wash your hands thoroughly with soap and water. Use a mirror or have someone else put the drops in your eye. Remove the protective cap. Make sure that the end of the dropper is not chipped or cracked. Avoid touching the dropper tip against your eye or anything else. Hold the dropper tip down at all times to prevent drops from flowing back into the bottle and contaminating the remaining contents. Lie down or tilt your head back. Holding the bottle between your thumb and index finger, place the dropper tip as near as possible to your eyelid without touching it. Brace the remaining fingers of that hand against your cheek or nose. With the index finger of your other hand, pull the lower lid of the eye down to form a pocket. Drop the prescribed number of drops into the pocket made by the lower lid and the eye. Placing drops on the surface of the eyeball can cause stinging. Close your eye and press lightly against the lower lid with your finger for 2-3 minutes to keep the medication in the eye. Do not blink. Replace and tighten the cap right away. Do not wipe or rinse it off. Wipe off any excess liquid from your cheek with a clean tissue. Wash your hands again.
The combination of amlodipine and benazepril is used to treat high blood pressure. Amlodipine is in a class of medications called calcium channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. Benazepril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly.How to use Amlodipine and benazepril OralTake this medication by mouth, usually once a day with or without food, or as directed by your doctor. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day.Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can raise your potassium levels, which rarely can cause serious side effects such as muscle weakness or very slow heartbeats. Tell your doctor immediately if these effects occur.The dosage is based on your medical condition and response to therapy. It may take 1 to 2 weeks before the full benefit of this drug occurs.It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Bisoprolol is used alone or in combination with other medications to treat high blood pressure. Bisoprolol is in a class of medications called beta blockers. It works by slowing the heart rate and relaxing the blood vessels so the heart does not have to pump as hard.Bisoprolol comes as a tablet to take by mouth. It is usually taken once a day. To help you remember to take bisoprolol, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take bisoprolol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Your doctor will probably start you on a low dose of bisoprolol and gradually increase your dose.Bisoprolol controls high blood pressure but does not cure it. It may take a few weeks before you feel the full benefit of bisoprolol. Continue to take bisoprolol even if you feel well. Do not stop taking bisoprolol without talking to your doctor. Suddenly stopping bisoprolol may cause angina (chest pain), heart attack, or irregular heartbeat.Your doctor will probably decrease your dose gradually. This drug is used to treat high blood pressure (hypertension). This medication is a combination of two drugs (an angiotensin receptor blocker and a thiazide "water pill"/diuretic). Irbesartan blocks the hormone angiotensin thereby relaxing blood vessels, causing them to widen. The thiazide diuretic increases the amount of urine you make, therefore decreasing excess water and salt in your body. High blood pressure reduction helps prevent strokes, heart attacks, and kidney problems.OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used to treat congestive heart failure and to help protect the kidneys from damage due to diabetes.How to use CoApprovel OralTake this medication by mouth, usually once daily or as directed by your doctor. You may take this drug with or without food. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day.Drink adequate fluids to prevent from becoming dehydrated. If you are on restricted fluid intake, consult your doctor for further instructions.Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can infrequently raise or lower your potassium blood levels, which rarely can cause serious side effects such as muscle weakness/cramping or very slow heartbeats. Tell your doctor immediately if these effects occur.The dosage is based on your medical condition and response to therapy. For the treatment of high blood pressure, it may take 2-4 weeks before the full benefit of this drug occurs.It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.If you are also taking cholestyramine or colestipol, take irbesartan/hydrochlorothiazide at least 2 hours before either of these drugs.CoApprovel Oral is used to treat the following:High Blood Pressure This product is able to be sourced and supplied at excellent prices because of favourable cross border currency conversions. All products are authentic brand names and will include a product information insert in English.Medical Information:Entacapone (in-TACK-a-pohn)is used in combination with levodopa/carbidopa to treat Parkinson's disease, sometimes referred to as shaking palsy. Some patients experience signs and symptoms of end-of-dose ôwearing-offö effect despite taking levodopa/carbidopa. Entacapone enhances the effect of levodopa/carbidopa. By improving muscle control, this medicine allows more normal movements of the body.Comtan is used for Parkinson's disease. It is prescribed when doses of the combination drug levodopa/carbidopa (Sinemet) begin to wear off too soon. By extending the effect of each dose of Sinemet, it frees the patient from the stiffness and tremors of Parkinson's for a longer period of time.Comtan works by inhibiting the effect of an enzyme that breaks down the levodopa in Sinemet. It has no effect on Parkinson's disease when used by itself.When used with levodopa and carbidopa, entacapone increases levels of levodopa (Dopar, Larodopa, Sinemet) in the body.Entacapone is used with carbidopa and levodopa to treat patients with Parkinson's disease who experience the signs and symptoms of end-of-dose "wearing-off". Entacapone is used only in combination with carbidopa and levodopa. It has no effect if it is used on its own.Treating Parkinson disease when used with levodopa/carbidopa.Comtan is a catechol-o-methyltransferase (COMT) inhibitor. It works by increasing the levels of levodopa/carbidopa in the brain, thereby enhancing its effectiveness. |